Electrostimulation Therapy (E-Stim)
Don’ take our word for it. What does the Research Say?
“..evaluated patients with both small and large fiber neuropathy and reported significant improvement in vibration and monofilament testing and reduction in symptoms in the electrical stimulation treatment group.”
Electrical Stimulation as an Adjunctive Treatment of Painful and Sensory Diabetic Neuropathy: Click Here
Electrical stimulation therapy for peripheral nerve injury Click Here
“Clinical studies have shown that electrical stimulation enhances axon growth during nerve repair and accelerates sensorimotor recovery.”
Unlocking nerve regeneration: electrical stimulation and bioscaffolds to enhance peripheral nerve regeneration: Click Here
“..we examine recent insights into key molecular mechanisms—particularly MAPK/ERK and PI3K/Akt—that govern Wallerian degeneration, Schwann cell (SC) reprogramming, and macrophage polarization. These and other critical steps in the axonal regeneration process must be understood and navigated for a therapeutic approach to be successful. We highlight emerging therapeutic strategies, such as electrical stimulation (ES), which appears to work by activating many of these pro-regenerative gene networks, both in neurons and non-neuronal support cells.”
“We postulate that integrating optimized ES protocols with innovative scaffold designs will allow for synergies to further enhance axonal regeneration and functional recovery.”
Application of electrical stimulation for peripheral nerve regeneration: Stimulation parameters and future horizons: Click Here
“Peripheral nerve regeneration is an intricate process – from axonal extension, guidance, and entry into the distal segment with the modulation of trophic support and remyelination – each step has its own significance. While ES increases the regenerative capacity, but in order to achieve successful regeneration, a multifaceted approach that targets the different aspects of regeneration is essential to achieve successful results.”
Accelerated axon outgrowth, guidance, and target reinnervation across nerve transection gaps following a brief electrical stimulation paradigm: Click Here
“..ES is associated with a 30%–50% improvement in several indices of regeneration: regrowth of axons and their partnered Schwann cells across transection sites, maturation of regenerated fibers in gaps spanning transection zones, and entry of axons into their muscle and cutaneous target zones.”