Low-Level Light (LLLT) Therapy
Don’ take our word for it. What does the Research Say?
“According to the data presented, it was concluded that LLLT has positive effects on the control of analgesia for neuropathic pain...”
Use of low level laser therapy to control neuropathic pain: A systematic review: Click Here
“There was a significant increase in Vitamin D and Magnesium levels after LLLT.”
Effect of Low Level Laser Therapy on serum vitamin D and magnesium levels in patients with diabetic peripheral neuropathy - A pilot study: Click Here
Low level light therapy/photobiomodulation for diabetic peripheral neuropathy: protocol of a systematic review and meta-analysis: Click Here
“The red and NIR light is mostly absorbed by the mitochondrial enzyme (ie, cytochrome-c-oxidase), the key chromophore in the cellular response to LLLT, to increase ATP production, modulation of reactive oxygen species (ROS) and the induction of transcription factors.”
Photobiomodulation therapy for peripheral neuropathy in diabetic and cancer patients: A narrative review: Click Here
“Peripheral neuropathy is a common and debilitating complication frequently observed in diabetic patients and individuals undergoing chemotherapy and radiotherapy for cancer treatment.”
“Current evidence suggests that PBMT may reduce neuropathic pain, improve nerve conduction, enhance sensory function, and improve quality of life in patients with DPN and CIPN. PBMT has also demonstrated beneficial effects on neurobiological biomarkers, including calcitonin gene-related peptide and neuron-specific enolase. In addition, its anti-inflammatory and mitochondrial regulatory effects may contribute to nerve regeneration and tissue repair.”
“PBMT represents a promising non-invasive therapeutic strategy for peripheral neuropathy management in diabetic individuals and cancer patients.”
Photobiomodulation Therapy (PBMT) in Peripheral Nerve Regeneration: A Systematic Review: Click Here
“..it was observed that PBMT was able to accelerate the process of nerve regeneration, presenting an increase in the number of myelinated fibers and a better lamellar organization of myelin sheath, besides improvement of electrophysiological function, immunoreactivity, high functionality rate, decrease of inflammation, pain, and the facilitation of neural regeneration, release of growth factors, increase of vascular network and collagen.”
Prevention and reversal of neuropathic pain by near-infrared photobiomodulation therapy in male and female rats: Click Here
“The results showed that PBMT before versus after CCI injury yielded similar behaviors, effectively decreasing allodynia.”
Low-Level Light Therapy in Postherpetic Neuralgia: A Review of Mechanistic Insights and Clinical Implications: Click Here
“Across neuropathic pain models, LLLT elevates mechanical and thermal pain thresholds, attenuates inflammatory cytokine signaling, and promotes an immune cell phenotype shift toward an anti-inflammatory profile including M1-to-M2 macrophage polarization. LLLT also stabilizes membrane excitability by restoring Na⁺/K⁺-ATPase activity and modulating calcium dynamics, while supporting peripheral nerve repair via axonal regeneration.”